He has developed a new surgical technique to perform cataract surgery; Ranjan’s Modified Manual Small Incision Cataract Surgery (R-MSICS), Cartwheel Chop for Phacoemulsification Cataract Surgery & combined glaucoma & cataract surgeries (The Infinity Incision).
He is also the inventor of two surgical instruments, the Ranjan MSICS Marker and Carter (The Cartwheel Chopper).
Dr. Ranjan is prolific writer & speaker. He has authored more than thirty-seven publications in peer reviewed journals, one book & contributed four book chapters.
He often serves as an invited guest speaker & trainer in various national & international conferences.
Till now he has mentored many young Indian and international ophthalmologists in Cataract & Glaucoma surgeries during their fellowship with him.
Currently, Dr. Ranjan is working at ASG Eye Hospital, Varanasi as Medical Director and Cataract, Refractive & Glaucoma Specialist with special interest in Medical Retina and Oculoplasty.
He runs an NGO, The Asoka Foundation to promote eye health and eradicate preventable blindness in the society.
Innovations
1) R-MSICS (Ranjan’s Technique of Manual Small Incision Cataract Surgery)
Modified MSICS technique to reduce time taken (not at the cost of quality) and improve outcomes. The flap-less tunnel making saves precious limbal stem cells, no use of dye (trypan blue) saves corneal endothelium, less instrumentation incites lesser inflammation leading to quicker & better visual recovery. It is also economical making it ideal and cost effective for poor. R – MSICS can be done more predictably & easily using Ranjan MSICS marker.
2) Ranjan MSICS Marker
It is created to help in three critical steps of Manual Small Incision Cataract Surgery (MSICS). It will fix the globe through its 360 serrated edges during tunnel making, It will help create perfect frown shaped 6mm incision exactly 2 mm away from limbus through its tunnel incision marker and the incorporated Corneal axis marker will help plan incision on steeper axis, taking care of pre existing astigmatism & SIA. This will make topical SICS a reality for majority of eye Surgeons practising SICS with ease and predictable outcome.
3) Cartwheel Chop: won the Timeless Tip Award from the Cataract & Refractive Surgery Today (CRST), USA in 2022
It is a technique developed for nucleus sculpting during Phacoemulsification cataract surgery for budding Phaco surgeons & hard cataract. In cartwheel chop, Phaco probe is impelled in the centre of the lens to fix it (like hub of cartwheel), with a Kelman 45 degree phaco tip one can rotate the lens like cartwheel and sculpt it using chopper over the imaginary spoke. . The nucleus after being impelled with phaco tip is lifted and tilted obliquely. The chopping happens at iris plane, the nuclear fragments are pushed back in the bag, while rotating and chopping. Creating 6 to 8 pieces. Fragments are then emulsified in the bag.
4) Topical Hepta Procedure
Featured on prestigious Eyetube, an USA based Ophthalmic surgery teaching video library
The Topical Hepta Procedure encompasses Trabeculectomy with Mitomycin C, Ologen and Anti VEGF along with Phacoemulsification and Intraocular Lens Implantation With Posterior Sub Tenon Triamcinolone
It is an excellent technique with quick recovery of vision and excellent Intraocular Pressure control with fewer immediate and long term complications.
5) Carter
The Cartwheel chopper for Phacoemulsification Surgery. Its unique feature include a blunt tip to ensure posterior capsule protection, sharp cutting edge for smooth chopping, a curve to lift nucleus for supracapsular chopping with more precision as curve will engage equator of cataractous lens and this smooth curve will also ensure Continuous Curvilinear Capsulorhexis margin protection.
6) Infinity Incision
Infinity incision is a modification of incision placed for SICS with Trab surgery for grade IV and above nucleus. It is a “V” incision with curved and longer horizontal limbs.
Research
1. “Feasibility study on injury and road traffic injury surveillance”, MC Mishra, Amit Gupta, Lalit Singh, Gyan Saurabh, Pratyush Ranjan, Mukesh Kumar, funded by Ministry of Health & Family Welfare; India, World Health Organization (WHO) & Indian Council of Medical Research (ICMR). (2007)
2. Thesis titled “Evaluation of macula by optical coherence tomography after uncomplicated cataract surgery with posterior chamber intraocular lens implantation by manual versus phacoemulsification small incision cataract surgery” under Professor L Sarkar. Accepted by the National Board of Examination, New Delhi in partial fulfillment of the requirement for the degree of Dipolmate of National Board of examination (ophthalmology) (2008-2011).
3. “Sitapur Corneal Ulcer Study Group (SCUSG)” Madhu Bhadauria, VK Pal, Pratyush Ranjan, Deepak Mishra, Shruti Gandhi, Deepak Singh funded by Sitapur eye hospital, Sitapur, Uttar Pradesh, India. (2012-2014)
4. “Sitapur Trachoma Study Group (STSG)” Madhu Bhadauria, VK Pal, Pratyush Ranjan, Deepak Mishra, Shruti Gandhi, Deepak Singh funded by Sitapur eye hospital, Sitapur, Uttar Pradesh, India. (2012-2014)
5. “Sitapur Vitamin A deficiency Study Group (SVADSG)”, Madhu Bhadauria, VK Pal, Pratyush Ranjan, Deepak Mishra, Shruti Gandhi, Deepak Singh funded by Sitapur eye hospital, Sitapur, Uttar Pradesh, India. (2012-2014)
6. “Comparison of refractive outcomes after phacoemuslification surgery with intraocular lens power calculation using ultrasound biometry and partial coherence laser interferometry (IOL Master)” Madhu Bhadauria, Pratyush Ranjan, Deepak Mishra. (2013-2014)
7. Co-Guide for the thesis, titled “Knowledge, Attitude and Practice regarding cataract and barriers in cataract surgery uptake- A cross-sectional study in tertiary care hospital in Bareilly district”, for partial fulfillment of degree of MD Community Medicine from Mahatma Jyotiba Phule Rohilkhand University, Bareilly. (Name of the candidate: Dr. Pankaj Kumar).
Publications
Books
1. “Visual outcome after MSICS & Phacoemulsification surgery” Pratyush Ranjan, Lopmudra Sarkar, KPS Malik. Lambert Academic Publications, Germany. August 2012 [ISBN: 978-3-659-21962-7]
2. “Post-Operative Care after Small Incision Cataract Surgery” Pratyush Ranjan, Divya Manohar. Master’s Guide manual SICS. ISMSICS, 2018
3. “Ocular Trauma” Pratyush Ranjan, Deepak Mishra, Satanshu Mathur. Essentials in Ophthalmology, Elsevier, India. 2019 [ISBN: 978-81-312-5005-1]
Original Research Papers
1. Bhavya Gokani, Pratyush Ranjan, Aniket Narendra Shastri. Cartwheel Chop. Cataract and Refractive Surgery Today, 2023; January: 63-64.
2. Mishra D, Dixit N, Ranjan P. One step beyond tomorrow; Ranjan manual small-incision cataract surgery (MSICS) marker – Welcome to the topical, flapless and astigmatism-free MSICS era. Indian J Ophthalmol. 2022 Nov;70(11):4086-4088. doi: 10.4103/ijo.IJO_1696_22. PMID: 36308169; PMCID: PMC9907308.
3. Pratyush Ranjan, Pavan Joshi, Malvika Gupta. Staphylococcus aureus Induced Endogenous Endophthalmitis with Pink Hypopyon. Ocular Immunology & Inflammation, 2016; 00(00): 1–2
4. Shobhana Dube, Pratyush Ranjan, V. Rajshekhar. Multidermatomal herpes zoster ophthalmicus in an immunocompetent male. Journal of Clinical Ophthalmology and Research. 5:1, 38-40. 2017
5. Madhu Bhadauria, Pratyush Ranjan, Deepak Mishra. Primary orbital plasmacytoma mimicking lacrimal gland tumor. Orbit. Aug;33(4):305-7. 2014
6. Pratyush Ranjan, Deepak Mishra, Madhu Bhadauria. Atoll sign in Posterior Lenticonus: A case report of bilateral Posterior Lenticonus with review of literature. Journal of Clinical Ophthalmology and Research. 2:3, 152-154. 2014
7. Anurag Narula, B. P. Guliani, Pratyush Ranjan, Aniket Shastri, K. P. S. Malik. Study The Correlation between Severity of Diabetic Retinopathy with Control and Duration of Diabetes. J of Evolution of Med and Dent Sci. 3:23, 6413-6423. 2014
8. Deepak Mishra, Pratyush Ranjan, VK Pal, Madhu Bhadauria. Epidemiology of Trachoma: A report by Sitapur Trachoma Study Group. J Clin Exp Ophthalmol. 5:2. 336-337. 2014.
9. Ritusha Mishra, Himanshu Mishra, Deepak Mishra, Pratyush Ranjan. Congenital Orbital Teratoma: A Rare Presentation. Int J Ophthalmic Pathol. 3:1. 2014
10. Anurag Narula, BP Guliani, HS Sethi, Pratyush Ranjan, Aniket Shastri, Vishnu Gupta. Juxtapapillary Hemangioblastoma: Case Report and Review of Literature. Delhi Journal of Ophthalmology. 24:3.195-198.2014
11. Pratyush Ranjan, Deepak Mishra, Arun D Singh, VB Pratap. Familial Moniliform Blephrosis: Clinical, Histopathological and Genetic Correlation. Ophthalmic genetics 0: 1-5. 2013
12. Pratyush Ranjan, BP Guliani, Moncef Khairallah, Deepak Mishra. Acute necrotizing Pan ophthalmitis in seropositive case of Chikungunya. Journal of Clinical Ophthalmology and Research.1:1. 23-25. 2013
13. Deepak Mishra, Pratyush Ranjan, B.P.Sinha, Vijay Baijal, Madhu Bhadauria. Retinoblastoma with unusual association of post-axial polydactyly. European journal of ophthalmology 23.5: 776-778. 2012
14. BP Guliani, Pratyush Ranjan, Anurag Narula, Shashi Khare. Acute Hemorrhagic Conjunctivitis by Enterovirus 71. Delhi Journal of Ophthalmology. 22:1.49-50. 2011
15. Pratyush Ranjan, Gyan Saurabh, Amit Gupta, Rahul Bansal. HIFU Vs Cryotherapy as primary treatment for Prostate cancer. IJU: 24.1: 16-21. 2008
16. Pratyush Ranjan. R-MSICS. Bihar Journal of Ophthalmology, 42:1. 24 -27, 2017.
17. Pratyush Ranjan. Ranjan MSICS Marker: The Beginning of Topical, Flapless, Astigmatism Free MSICS Era. DOS Times, March – April 2017; 56 – 57.
18. Pankaj Kumar, Hari S Joshi, Rashmi Katyal, Pratyush Ranjan. An Epidemiological Study on Perception of the Cataract Patients regarding Cataract Surgery in Tertiary Care Hospital, Bareilly District, Uttar Pradesh – Original Article. International Journal of Advanced & Integrated Medical Sciences. Vol 1, Issue 4; 2016, 148 – 150.
19. Pratyush Ranjan, Deepak Mishra. Updates on Implants in Glaucoma Surgery. Highlights of Ophthalmology. 42:1. 10-13. 2014.
20. Pratyush Ranjan, Vibha Singh, Deepak Mishra, Anurag Narula. Phthiriasis Palpebrarum: A rare disease with rare presentation as squamous blephroconjunctivitis. Journal of Ophthalmic Photography. 36:1, 39-41. 2014
21. Pratyush Ranjan, Deepak Mishra, Nilesh Mohan, B.P. Sinha. Fungal Conjunctivitis. DOS Times.19: 9, 57-58. 2014
22. Deepak Mishra, Pratyush Ranjan, Shruti Gandhi, Vijay Baijal, Madhu Bhadauria. Caterpillar Hair Induced Ophthalmitis. Highlights of Ophthalmology (English & Spanish Edition). 41:4, 10-11. 2013
23. Pratyush Ranjan, Shruti Gandhi, Deepak Mishra, Vijay Baijal, Madhu Bhadauria. Trachoma: A still unconquered scourge. Bihar journal of Ophthalmology. 37, 62-63. 2012.
24. Pratyush Ranjan, RN Das. Picture Quiz – Hydatid Disease. Student BMJ. 14, 441-484. 2006
25. HS Joshi, MC Joshi, Pratyush Ranjan, S Mishra, P Verma, G Agarvanshi, MSS Rana. Refresher Training on Maternal and Child Health for Urban Community Health Volunteers: Assessing Knowledge and Skills. Internet Journal of Medical Update (Mauritius).1:2. 2006
Member of Professional Bodies
International Society for Manual Small Incision Cataract Surgeons
European Society of Cataract & Refractive Surgeons (ESCRS): 613282
All India ophthalmological Society (AIOS): R13939
Delhi ophthalmological society (DOS): R3922
Bihar Ophthalmological Society (BOS): R662
Uttar Pradesh State Ophthalmological Society (UPSOS): R64
